UK Drug Safety Update is an official public source that HealthSignal monitors for Pharmaceuticals, General Regulatory. The most recent updates we have tracked from it are listed below, each normalised into our index and linked back to the original publication on the source's own website.
Healthcare professionals should be aware of the potential for delayed onset of angioedema and the distinction between bradykinin- and histamine-mediated cases, as treatment strategies differ significantly and bradykin...
UK Drug Safety UpdateThere have been reports of worsening nasal congestion (rebound congestion) when the effects of nasal decongestant sprays or drops containing xylometazoline hydrochloride and oxymetazoline hydrochloride, wear off.
UK Drug Safety UpdateNon-arteritic anterior ischemic optic neuropathy (NAION), a condition that can cause sudden deterioration in vision, usually in one eye at a time, has been very rarely reported in association with semaglutide in the t...
UK Drug Safety UpdateThere is a risk of patient harm arising through medication error during a transition period where the original and new formulation of Rybelsus ® tablets, which have different stated mg doses but are bioequivalent, wil...
UK Drug Safety UpdatePatients should be reminded and reassured that there is no evidence that taking paracetamol during pregnancy causes autism in children. Paracetamol is recommended as the first-choice pain reliever for pregnant women, ...
UK Drug Safety UpdateA summary of recent letters and notifications sent to healthcare professionals about medicines and medical devices, and information about the publication of two recent Device Safety Information pages. The article also...
UK Drug Safety UpdateThere is a small increase in the risk of Guillain-Barré syndrome following vaccination with Abrysvo (Pfizer respiratory syncytial virus (RSV) vaccine) and Arexvy (GSK RSV vaccine) in adults aged 60 years and older. H...
UK Drug Safety UpdateThe Commission on Human Medicines (CHM) has temporarily restricted use of the IXCHIQ Chikungunya vaccine in people aged 65 years and over following very rare fatal reactions reported globally. This is a precautionary ...
UK Drug Safety UpdatePsychological side effects such as anxiety, low mood, sleep disturbance, poor concentration, and forgetfulness have been infrequently reported in people with cystic fibrosis treated with Kaftrio. Healthcare profession...
UK Drug Safety UpdateHealthcare professionals and patients are reminded of the risk of severe asthma attacks and increased mortality associated with overuse of SABA with or without anti-inflammatory maintenance therapy in patients with as...
UK Drug Safety UpdateFezolinetant treatment is associated with a risk of drug induced liver injury. New recommendations have been introduced to minimise this risk. Liver function should be monitored before and during treatment in all pati...
UK Drug Safety UpdateThe indication for the treatment of post-operative pain has been removed from the licences of all prolonged release opioids due to the increased risk of persistent post-operative opioid use (PPOU) and opioid-induced v...
UK Drug Safety UpdateA summary of recent letters and notifications sent to healthcare professionals about medicines and medical devices.
UK Drug Safety UpdateA summary of recent letters and notifications sent to healthcare professionals about medicines and medical devices.
UK Drug Safety UpdateHealthcare professionals should be aware of the potential risk of pulmonary aspiration in patients using GLP-1 or dual GIP/GLP-1 receptor agonists who undergo surgery or procedures with general anaesthesia or deep sed...
UK Drug Safety UpdateA summary of recent letters and notifications sent to healthcare professionals about medicines and medical devices.
UK Drug Safety UpdateA summary of recent letters and notifications sent to healthcare professionals about medicines and medical devices.
UK Drug Safety UpdateWe ask healthcare professionals to support new guidance for users of diabetes management equipment, their families, care givers and representatives.
UK Drug Safety UpdateA summary of recent letters and notifications sent to healthcare professionals about medicines and medical devices.
UK Drug Safety UpdateA summary of recent letters and notifications sent to healthcare professionals about medicines and medical devices.
UK Drug Safety UpdateA summary of recent letters and notifications sent to healthcare professionals about medicines and medical devices.
UK Drug Safety UpdateA summary of recent letters and notifications sent to healthcare professionals about medicines and medical devices.
UK Drug Safety UpdateTaking warfarin and tramadol together can cause harmful drug interactions, which can raise the International Normalised Ratio (INR), and result in severe bruising and bleeding, which in some patients could be fatal.
UK Drug Safety UpdateA summary of recent letters and notifications sent to healthcare professionals about medicines and medical devices.
UK Drug Safety UpdateTopiramate is now contraindicated in pregnancy and in women of childbearing potential unless the conditions of a Pregnancy Prevention Programme are fulfilled. This follows a review by the MHRA which concluded that the...
UK Drug Safety UpdateAmiodarone has been associated with serious and potentially life-threatening side effects, particularly of the lung, liver, and thyroid gland. We remind healthcare professionals that patients should be supervised and ...
UK Drug Safety Update