New guidance for users of diabetes management equipment on reporting suspected adverse incidents and safety concerns via the Yellow Card scheme.
UK Drug Safety Update · UKHealthcare professionals advised to distinguish bradykinin- from histamine-mediated angioedema in ACE-inhibitor use, as treatment strategies differ significantly.
UK Drug Safety Update · UKMHRA reviewed and updated safety warnings on addiction, dependence, withdrawal and tolerance for gabapentinoids, benzodiazepines and z-drugs.
UK Drug Safety Update · UKMHRA reaffirms paracetamol safety in pregnancy and clarifies no evidence links it to autism in children.
UK Drug Safety Update · UKHealthcare professionals and patients reminded of risks of severe asthma attacks and increased mortality from SABA overuse, with updated prescribing guidance.
UK Drug Safety Update · UKAnnual awareness campaign promoting public reporting of suspected medicine and healthcare product safety problems to the Yellow Card scheme.
UK Drug Safety Update · UKPost-operative pain indication removed from all prolonged-release opioid licences due to risk of persistent opioid use and ventilatory complications.
UK Drug Safety Update · UKHealthcare professionals warned of pulmonary aspiration risk in patients on GLP-1 or GIP/GLP-1 agonists undergoing general anaesthesia or deep sedation.
UK Drug Safety Update · UKTwo-specialist review requirement for valproate initiation under 55 years removed for men already taking the medicine.
UK Drug Safety Update · UKHealthcare professionals reminded of serious and potentially life-threatening side effects of amiodarone, particularly affecting lung, liver, and thyroid; patient supervision and review required.
UK Drug Safety Update · UKWarfarin and tramadol together can cause harmful interactions, raising INR and risk of severe bleeding.
UK Drug Safety Update · UKIntrahepatic cholestasis of pregnancy rarely reported with thiopurine class drugs; new safety restriction advised for pregnant patients.
UK Drug Safety Update · UKTopiramate is now contraindicated in pregnancy and women of childbearing potential unless a Pregnancy Prevention Programme is fulfilled.
UK Drug Safety Update · UKRisk of medication error during transition period when original and new bioequivalent formulations with different stated doses are both in circulation.
UK Drug Safety Update · UKNon-arteritic anterior ischemic optic neuropathy (NAION) has been very rarely reported with semaglutide treatment.
UK Drug Safety Update · UKIdiopathic intracranial hypertension warnings being added to product information for all mesalazine products following safety review.
UK Drug Safety Update · UKProduct information updated to add contraindication for confirmed or suspected phaeochromocytoma due to severe hypertension risk.
UK Drug Safety Update · UKSafety alert on rebound congestion and rhinitis medicamentosa risk with overuse of nasal decongestant sprays and drops containing xylometazoline or oxymetazoline.
UK Drug Safety Update · UKSummary of healthcare professional letters and medicine recall notifications issued in April 2024.
UK Drug Safety Update · UKA summary of recent letters and notifications sent to healthcare professionals about medicines and medical devices.
UK Drug Safety Update · UKA summary of recent letters and notifications sent to healthcare professionals about medicines and medical devices.
UK Drug Safety Update · UKA summary of recent letters and notifications sent to healthcare professionals about medicines and medical devices.
UK Drug Safety Update · UKA summary of recent letters and notifications sent to healthcare professionals about medicines and medical devices.
UK Drug Safety Update · UKSmall increased risk of Guillain-Barré syndrome identified following RSV vaccination in adults aged 60 years and older.
UK Drug Safety Update · UKPsychological side effects including anxiety, low mood, sleep disturbance, poor concentration and forgetfulness reported infrequently in cystic fibrosis patients treated with Kaftrio.
UK Drug Safety Update · UKFezolinetant carries a risk of drug-induced liver injury; new monitoring recommendations introduced for all patients.
UK Drug Safety Update · UKClass 2 recall of WockAIR 160/4.5 microgram inhalation powder (Wockhardt) issued 9 December 2024 for defective top case preventing dose dispensing.
UK Drug Safety Update · UKClass 3 recall of Baclofen 10mg/5ml oral solution due to crystallisation; company-led recall of EXS Delay Spray Plus issued in November 2024.
UK Drug Safety Update · UKSummary register of safety letters and medicine recalls issued to healthcare professionals in August 2024.
UK Drug Safety Update · UKSummary register of safety letters and medicine recalls issued to healthcare professionals in July 2024.
UK Drug Safety Update · UKCHM temporarily restricts IXCHIQ Chikungunya vaccine use in people aged 65+ following very rare fatal reactions reported globally.
UK Drug Safety Update · UKUpdated safety and educational materials released to support implementation of regulatory measures on valproate reproductive risks announced in November 2023.
UK Drug Safety Update · UKClass 2 recalls issued for amlodipine tablets due to possible microbial contamination and cough relief products.
UK Drug Safety Update · UK