UK Drug Safety Update · June 16, 2026

ACE-inhibitors: distinction between bradykinin- and histamine-mediated angioedema and treatment strategies

Original title: ACE-inhibitors: Be aware of the distinction between bradykinin- and histamine-mediated angioedema, as treatment strategies differ significantly

Healthcare professionals advised to distinguish bradykinin- from histamine-mediated angioedema in ACE-inhibitor use, as treatment strategies differ significantly.

High obligation Sector Pharmaceuticals UK Pharmacovigilance

Healthcare professionals should be aware of the potential for delayed onset of angioedema and the distinction between bradykinin- and histamine-mediated cases, as treatment strategies differ significantly and bradykinin-medi…

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