Taking warfarin and tramadol together can cause harmful drug interactions, which can raise the International Normalised Ratio (INR), and result in severe bruising and bleeding, which in some patients could be fatal.
UK Drug Safety Update · June 20, 2024
Warfarin: be alert to the risk of drug interactions with tramadol
Warfarin and tramadol together can cause harmful interactions, raising INR and risk of severe bleeding.
Published by UK Drug Safety Update. HealthSignal links to the original document; the summary above is extracted from the source text.