The indication for the treatment of post-operative pain has been removed from the licences of all prolonged release opioids due to the increased risk of persistent post-operative opioid use (PPOU) and opioid-induced ventilat…
UK Drug Safety Update · March 12, 2025
Prolonged-release opioids: Removal of indication for relief of post-operative pain
Post-operative pain indication removed from all prolonged-release opioid licences due to risk of persistent opioid use and ventilatory complications.
Published by UK Drug Safety Update. HealthSignal links to the original document; the summary above is extracted from the source text.